"An aggregate of 8000 cells with initial random polarities unfolds into a stable complex morphology. During the simulation, the polarities and positions are updated dynamically with equal speed and noise (dt = 0.1 and η = 10−3). There is no planar cell polarity (λ1 = 1 and λ2 = λ3 = 0). (A) The entire system unfolds, and we notice that the outer surface reaches equilibrium state later than the internal morphology (see also Figure 3—figure supplement 2). (B) Cross-section of the system at y = 0. (C) Same as (B) but viewed from an angle slightly above and from a side. The color scheme is as described in Figure 3."
Citation: Nissen SB, Rønhild S, Trusina A, Sneppen K (2018) Theoretical tool bridging cell polarities with development of robust morphologies. eLife 2018(7): e38407.
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