Over-The-Counter Drugs: The Misuse of DXM

The misuse of Dextromethorphan (DXM) is common among teenagers and young adults. It is a common substance found in cough and cold over-the-counter medications such as Nyquil and Tylenol Cough & Cold. This video was created as an effort to increase awareness of the risks involved with misusing DXM.

Background music is courtesy of bdProductions on YouTube.

This video was made by McMaster Demystifying Medicine students Kiran Mann, Maleeka Munroe, Krizalyn Jacinto, Christine Okoh, and Angela Joo.


Copyright McMaster University 2019.


References:

Akerman, S. C., Hammel, J. L., & Brunette, M. F. (2010). Dextromethorphan abuse and dependence in adolescents. Journal of Dual Diagnosis, 6(3-4), 266-278.

Al-Kuraishy, H. M., Al-Gareeb, A. I., & Ashor, A. W. (2012). Effect of a single dose of dextromethorphan on psychomotor performance and working memory capacity. Indian journal of psychological medicine, 34(2), 140.

Aronson JK. Dextromethorphan. In: Aronson JK, ed. Meyler's Side Effects of Drugs. 16th ed. Waltham, MA: Elsevier; 2016:899-905.

Dextromethorphan (DXM) Abuse. (n.d.). Retrieved from

Dextromethorphan (DXM) Abuse and Addiction: Treatment, Symptoms, and Signs. (2019). Retrieved from

Ford, C., & Good, B. (2007). Over the counter drugs can be highly addictive. BMJ (Clinical research ed.), 334(7600), 917–918. doi:10.1136/bmj.39199.472326.3A

Over-the-Counter Medicines. (2017). Retrieved from

Reissig, C. J., Carter, L. P., Johnson, M. W., Mintzer, M. Z., Klinedinst, M. A., & Griffiths, R. R. (2012). High doses of dextromethorphan, an NMDA antagonist, produce effects similar to classic hallucinogens. Psychopharmacology, 223(1), 1–15. doi:10.1007/s00213-012-2680-6

Roy III, A. K., Hsieh, C., & Crapanzano, K. (2015). Dextromethorphan addiction mediated through the NMDA system: common pathways with alcohol?. Journal of addiction medicine, 9(6), 499-501.

Shadkam, M. N., Mozaffari-Khosravi, H., & Mozayan, M. R. (2010). A comparison of the effect of honey, dextromethorphan, and diphenhydramine on nightly cough and sleep quality in children and their parents. The Journal of Alternative and Complementary Medicine, 16(7), 787-793.

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